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Prescription Opioid Addiction Treatment

Opioids are a class of drugs naturally found in the opium poppy plant.
man sharing in a group therapy session

Table of Contents

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Jeremy Dubin
Clinically Reviewed By Dr. Jeremy Dubin
Porch Light Health is committed to helping individuals overcome prescription opioid addiction. Central to our approach is Medications for Addiction Treatment. We specialize in offering essential medications such as buprenorphine (often recognized by its brand name, Suboxone) and naltrexone, both of which play a significant role in the treatment of opioid addiction. Beyond medication, Porch Light Health integrates behavioral health and psychiatric services into its care model, ensuring a holistic strategy that encompasses both the physical and emotional facets of addiction.

Accessibility and inclusivity are core to our mission at Porch Light Health. With this in mind, we have established over 60 clinic locations throughout Colorado, with new locations opening in New Mexico. Recognizing the diverse needs of our patients, we've also introduced mobile clinics to cater to those who might find traditional settings less accessible. For those who prefer the convenience of online consultations or are located further away, our telehealth services ensure that quality care is always within reach.

With its comprehensive range of services and an expanding network, Porch Light Health remains a steadfast partner for many, guiding them toward a healthier and more fulfilling future.

What are prescription opioids?

Prescription opioids are powerful pain-relieving medications derived either directly from the opium plant or synthesized in laboratories to mimic its chemical structure. They are commonly prescribed to alleviate moderate to severe pain.

Some opioids also address conditions like coughing and diarrhea. However, their relaxing effects can lead to misuse, as they can induce feelings of euphoria or a "high." This misuse can be perilous, given the addictive nature of opioids and the associated risks of overdose and death. It's crucial to note that heroin, one of the most hazardous opioids, is not used medically in the U.S.

Commonly Prescribed Opioids Include:
  • Hydrocodone (e.g., Vicodin®): Hydrocodone is a semi-synthetic opioid derived from codeine. It's commonly prescribed for moderate to severe pain relief and is often combined with other non-opioid analgesics like acetaminophen.
  • Oxycodone (e.g., OxyContin®, Percocet®): Oxycodone is a semi-synthetic opioid made from thebaine, a naturally occurring substance in the opium poppy. It's used to treat moderate to severe pain. OxyContin® is a time-release version, while Percocet® combines oxycodone with acetaminophen.
  • Oxymorphone (e.g., Opana®): Oxymorphone is a semi-synthetic opioid derived from thebaine. It's prescribed for pain management and offers extended-release pain relief.
  • Morphine (e.g., Kadian®, Avinza®): Morphine is a natural opioid derived from the opium poppy. It's one of the oldest and most potent pain relievers available. Kadian® and Avinza® are brands that offer extended-release formulations of morphine.
  • Codeine: Codeine is a natural opioid and is less potent than morphine. It's often prescribed for mild to moderate pain and is also used as a cough suppressant in certain medications.
  • Fentanyl: Fentanyl is a synthetic opioid that is 50 to 100 times more potent than morphine. It's used for treating severe pain, often in patients who have developed a tolerance to other opioids. It's available in various forms, including patches, lozenges, and injectables.

How do people misuse prescription opioids?

Prescription opioids, while invaluable in the realm of pain management, come with a risk. Their efficacy in alleviating pain is undeniable, but so is their potential for misuse. This misuse not only jeopardizes the health of the individual but also poses broader societal challenges. To fully grasp the magnitude and nuances of this issue, it's essential to delve into the various ways opioids can be misused:

Altering Prescribed Dosage or Method

Some individuals might consume the medication in doses higher than recommended or use it more frequently than instructed. This deviation from the prescribed regimen can increase the risk of adverse effects and dependency.

Using Someone Else's Medication

Borrowing or taking another person's prescription opioids is a form of misuse. Every prescription is tailored to an individual's specific needs, and using someone else's medication can lead to unintended consequences.

Recreational Use

Some individuals consume prescription opioids not for pain relief but for the euphoric or "high" sensation they produce. This recreational use can quickly lead to addiction and other health complications.

Alternative Consumption Methods

While the standard method of taking prescription opioids is oral ingestion, some misusers resort to alternative methods to achieve a more potent or rapid effect. For instance:
  • Crushing and Snorting: By crushing the pills into a fine powder and inhaling it through the nose, individuals can experience a quicker onset of effects.
  • Dissolving and Injecting: Some go to the extent of dissolving crushed pills in water and injecting the solution directly into their bloodstream. This method poses additional risks, including infections and damage to veins.
  • Smoking: Another method involves smoking crushed opioid pills, which can lead to rapid absorption into the bloodstream through the lungs. This method also carries risks, including respiratory issues and potential exposure to harmful byproducts.
It's crucial to understand and recognize these misuse patterns to ensure the safe and effective use of prescription opioids. Proper education and awareness can play a significant role in preventing opioid-related complications.

How do Prescription Opioids Affect the Brain?

Prescription opioids have a profound effect on the brain and its intricate network of neurons. At the core of their action lies their ability to interact with specific proteins called opioid receptors. These receptors are scattered throughout the brain, spinal cord, and various other organs, playing pivotal roles in modulating sensations of pain and pleasure.

When an individual consumes opioids, these drugs seek out and bind to the opioid receptors. This binding action serves a dual purpose:
  • Pain Modulation: By attaching to these receptors, opioids effectively interrupt the transmission of pain signals from various parts of the body to the brain. This results in the individual experiencing reduced sensations of pain, even if the underlying cause of the pain remains unchanged.
  • Dopamine Release: Beyond just pain modulation, opioids also stimulate the release of dopamine, a neurotransmitter associated with pleasure, reward, and motivation. This surge of dopamine creates feelings of euphoria and well-being. However, it's this very release that can be problematic. The intense pleasure derived from the dopamine surge can make the experience of taking opioids highly rewarding, creating a powerful psychological incentive for individuals to continue using the drug or even increase their dosage.
Over time, as the brain becomes accustomed to these regular dopamine surges, it may come to crave the drug, leading to repeated use and, in some cases, the development of dependency or addiction. Understanding this neurological impact is crucial for both medical professionals prescribing these medications and patients consuming them, ensuring that opioids are used responsibly and effectively.

What are some possible effects of prescription opioids on the brain and body?

Prescription opioids, while primarily designed for pain management, exert a range of effects on both the brain and the body. Their influence spans from providing immediate relief to potential long-term complications.

Beneficial Effects

  • Pain Relief: Opioids are potent analgesics, meaning they can significantly reduce or eliminate pain, making them invaluable for individuals suffering from acute or chronic pain conditions.
  • Relaxation and Calm: Beyond just pain relief, opioids can induce a sense of relaxation, helping to alleviate anxiety and tension.
  • Euphoria: Some individuals experience heightened feelings of happiness or euphoria when taking opioids, which can contribute to their potential for misuse.

Adverse Effects

  • Drowsiness: Opioids can cause significant sedation, making activities like driving or operating heavy machinery dangerous.
  • Confusion: Cognitive functions can be impaired, leading to confusion or difficulty in making decisions.
  • Nausea: Some individuals might experience an upset stomach or a feeling of wanting to vomit.
  • Constipation: Opioids can slow down the digestive system, leading to constipation, which can become severe if not addressed.
  • Respiratory Depression: One of the most concerning side effects is slowed breathing. This can reduce the amount of oxygen that reaches vital organs, including the brain.

Severe Consequences of Misuse

  • Hypoxia: Prolonged respiratory depression can lead to hypoxia, a condition where the brain doesn't receive enough oxygen. This can result in a range of complications, from dizziness and confusion to more severe outcomes like coma, irreversible brain damage, or even death.
  • Long-term Neurological Effects: Chronic misuse of opioids can alter the brain's structure and function. Researchers are delving deep into understanding these changes, especially to determine if any of the damage can be reversed or if there are lasting cognitive impairments.
Given these varied effects, it's crucial for both healthcare providers and patients to approach opioid use with caution, ensuring they are used responsibly and with a clear understanding of their potential risks and benefits.

What are the other health effects of opioid medications?

Opioid medications, while beneficial for pain management, come with a spectrum of health effects that can vary among individuals. Particularly, certain populations, like older adults, may face unique risks due to their specific health profiles and lifestyles.

Risks for Older Adults

  • Accidental Misuse or Abuse: The elderly population often manages multiple health conditions, leading them to juggle various medications. This increases the chances of unintentionally misusing opioids, either by taking incorrect doses or mixing them with other medications.
  • Drug Interactions: With multiple prescriptions, the likelihood of drug-drug interactions rises. Some medications can amplify the effects of opioids, while others might reduce their efficacy.
  • Disease Interactions: Chronic conditions prevalent in older adults can be exacerbated by opioid effects. For instance, a person with respiratory issues might face increased breathing difficulties when taking opioids.
  • Metabolic Changes: As we age, our body's ability to metabolize drugs can slow down. This means that opioids might remain in an older person's system for longer, increasing the risk of side effects or overdose.

Severe Consequences of Misuse

  • Risk of Infectious Diseases: Sharing injection equipment, a practice some opioid misusers might engage in, significantly raises the risk of contracting blood-borne infections like HIV or hepatitis.
  • Impaired Judgment and Risky Behaviors: Opioids can cloud judgment, leading to risky behaviors. For instance, an individual under the influence might engage in unprotected sex, increasing the risk of sexually transmitted infections.
Understanding these diverse health implications is crucial for both healthcare providers prescribing these medications and patients consuming them. Proper education, regular monitoring, and open communication can help mitigate these risks and ensure the safe use of opioid medications.

What is Opioid Use Disorder (OUD)?

Opioid Use Disorder (OUD) is a medical condition characterized by a detrimental pattern of opioid consumption that disrupts an individual's daily life. It's more than just a physical reliance on opioids; it encapsulates a range of behavioral, psychological, and physiological factors that can have profound implications for an individual's well-being.

While "Opioid Use Disorder" is the medically recognized term, other phrases like "opioid dependence" and "opioid addiction" are sometimes used interchangeably, though they highlight different aspects of the disorder:
  • Opioid Dependence: This primarily refers to the physical aspect of the disorder. An individual who is dependent on opioids will experience withdrawal symptoms when they stop or reduce their intake. These symptoms can range from mild discomforts, like irritability and cravings, to severe physical symptoms, such as muscle pain, nausea, and agitation.
  • Opioid Addiction: This term delves deeper into the psychological realm. Addiction is a chronic brain disease that alters the way the brain functions, leading to compulsive drug-seeking behaviors. An individual with an opioid addiction will continue to use the drug despite being fully aware of the harmful consequences it brings.
Recognizing and understanding OUD is the first step toward seeking appropriate treatment and support. With the right interventions, individuals can manage their condition and lead fulfilling lives.

Can a Person Overdose on Prescription Opioids?

Absolutely. Overdosing on these medications happens when an individual consumes a quantity that is sufficient to induce severe, potentially fatal symptoms. One of the most alarming effects of an opioid overdose is respiratory depression, where the person's breathing becomes dangerously slow or even halts altogether. This lack of adequate oxygen flow can starve the brain, leading to severe consequences such as falling into a coma, sustaining irreversible brain damage, or, in the worst cases, death.

Recognizing the Signs and Symptoms of an Opioid Overdose

An opioid overdose is a critical medical emergency. Recognizing the signs of overdose can be the difference between life and death. Here are the key symptoms to watch out for:
  • Shallow or Labored Breathing: One of the most telling signs of an opioid overdose is respiratory depression. The person's breathing may become very slow, irregular, or may stop altogether.
  • Pinpoint Pupils: The individual's pupils may become very small, often described as "pinpoint."
  • Loss of Consciousness: The person might become unresponsive or may not wake up even when prompted.
  • Bluish or Pale Skin: Due to decreased oxygen in the blood, the skin, especially around the lips and fingernails, may take on a bluish or pale hue.
  • Limp Body: Muscles may become slack, causing the individual to appear limp or lifeless.
  • Vomiting or Gurgling Noises: Some individuals may vomit, or you might hear an abnormal gurgling sound.
  • Slow or Irregular Heartbeat: The heart rate may decrease significantly or become erratic.
  • Low Body Temperature: The individual might feel unusually cold to the touch, signaling a drop in body temperature, often referred to as "cold and clammy skin."
  • Confusion or Disorientation: If still conscious, the person might appear extremely confused, drowsy, or unable to speak clearly.
If you observe any combination of these symptoms, it's essential to act immediately. Call emergency services and, if available and you are trained to do so, administer naloxone. Always stay with the individual until medical professionals arrive, and place them in the recovery position (on their side) to prevent potential choking if they vomit.

How Can an Opioid Overdose Be Treated?

In the face of an opioid overdose, rapid and informed action is of paramount importance. Recognizing the signs and being equipped with the knowledge of the right steps to take can be life-saving.

The initial and most crucial response when suspecting an opioid overdose is to call emergency services by dialing 911. Immediate medical intervention is pivotal to ensure the best possible outcome. Upon the arrival of medical professionals, they may opt to administer a drug known as naloxone. This medication is tailor-made to counteract the life-threatening effects of an opioid overdose. Its mechanism of action is swift and effective; it attaches to the opioid receptors in the brain, blocking and reversing the impact of the opioid drugs.

Naloxone's versatility is noteworthy. It can be administered in a variety of ways, each designed for ease of use and rapid response. The traditional method involves an injectable solution delivered directly into the bloodstream. For those without medical training, there's the hand-held auto-injector EVZIO®, which simplifies the injection process. Alternatively, the NARCAN® Nasal Spray offers a non-invasive approach, delivering the drug as a mist into the nostrils.

In a proactive move to combat the opioid crisis, several states have enacted laws that allow pharmacists to provide naloxone without a direct prescription. This initiative empowers community members, especially friends and family of those at risk, to have naloxone readily available. FRC Clinics are readily stocked with Narcan and it is regularly distributed to patients and their family members.. This accessibility ensures that in the critical moments following an overdose, immediate action can be taken even before medical professionals arrive on the scene. Awareness, education, and accessibility form the triad in our collective efforts to reduce opioid-related fatalities.

Can the Use of Prescription Opioids Lead to Addiction?

Prescription opioids, while beneficial for pain management, carry a risk of leading to addiction, especially when misused. Over time, consistent misuse of these medications can culminate in a substance use disorder (SUD), a medical condition that varies in intensity from mild to severe and can be either short-lived or chronic. At its most extreme, addiction represents the most intense manifestation of an SUD.

The development of an SUD is not merely about the physical cravings for the drug. It's a complex interplay of physiological and psychological changes. Prolonged misuse can alter the brain's chemistry and structure, leading to health complications and an inability to fulfill responsibilities in personal and professional spheres, including at work, school, or within the family.

For those who become addicted to opioid medications, discontinuation can be a daunting challenge. Withdrawal symptoms can manifest within hours of the last dose and can be both physically and mentally agonizing. Common symptoms include:
  • Intense muscle and bone pain
  • Disruptions in sleep patterns
  • Gastrointestinal issues like diarrhea and vomiting
  • Chilling sensations accompanied by goosebumps
  • Involuntary leg movements
  • Overpowering drug cravings
The severity and discomfort of these symptoms often deter individuals from attempting to quit, trapping them in a cycle of dependency. However, strides are being made in medical science to alleviate this challenging phase. The U.S. Food and Drug Administration (FDA) has given its nod to the NSS-2 Bridge device, a novel approach to managing withdrawal symptoms. This compact electrical nerve stimulator, positioned behind the ear, offers relief during the acute withdrawal phase, typically lasting up to five days.

In addition to devices, new pharmaceutical interventions are also on the horizon. Brixadi is an extended-release injection that the FDA has recently approved to treat moderate to severe opioid use disorder (OUD). Brixadi is available in two formulations, weekly and monthly, for patients already being treated with buprenorphine.

FRC medical providers within the outpatient clinics can safely triage and manage withdrawal with medications and appropriate monitoring. Inpatient needs for medical detoxification are triaged at every visit.

What Treatment Is Available for Prescription Opioid Addiction?

Prescription opioid addiction is a complex issue, but with the right interventions, recovery is attainable. A holistic approach, combining both medical and behavioral therapies, has been shown to be particularly effective in addressing the multifaceted nature of opioid addiction.

Medicinal Interventions

  • Buprenorphine: Buprenorphine is the primary medication employed in the treatment of opioid addiction. Its mechanism of action involves binding to the same opioid receptors in the brain that are activated by opioid drugs. Doing so can help significantly reduce cravings and the often debilitating withdrawal symptoms that many individuals face when trying to quit opioids.
  • Naltrexone: Unlike buprenorphine and methadone, naltrexone functions by blocking opioid receptors. This means that even if someone takes an opioid drug while on naltrexone, they won't experience the usual euphoric effects, making it a deterrent to relapse.

Behavioral Therapies

Behavioral therapies play a pivotal role in addressing the psychological aspects of addiction. They aim to reshape attitudes, behaviors, and coping strategies related to drug use:
  • Cognitive Behavioral Therapy (CBT): CBT is a widely recognized approach that focuses on helping patients recognize and challenge their patterns of thought and behavior related to drug use. By understanding and modifying these patterns, individuals can better manage triggers, stress, and temptations that might lead to relapse.
  • Contingency Management (CM): This therapeutic approach rewards patients for desired behaviors, such as maintaining sobriety. By providing tangible rewards for drug-free urine tests or consistent therapy attendance, CM reinforces positive behaviors and encourages continued commitment to recovery.
Incorporating both medicinal and behavioral therapies offers a comprehensive treatment plan. This dual approach not only addresses the physical dependencies but also equips individuals with the psychological tools they need to navigate a life free from addiction.

Help is Available at Porch Light Health

The complex nature of prescription opioid dependency, encompassing aspects of tolerance, addiction, and the ever-evolving landscape of opioid types, underscores the need for a nuanced understanding and approach. As the opioid crisis has transformed, from the initial surge in pain medication prescriptions to the emergence of potent synthetic opioids, the need for reliable and compassionate care has never been greater.

Porch Light Health stands as a beacon for those seeking guidance and support in their journey towards recovery. If you or someone close to you are grappling with opioid addiction, remember that you don't have to navigate this path alone. The dedicated professionals at Porch Light Health are equipped and eager to assist, offering a comprehensive toolkit to help assist someone in their overall well being, recovery and functionality. 

Every transformative journey starts with a single, decisive step. Let Porch Light Health be your trusted companion as you embark on your journey toward a brighter, healthier tomorrow. Call us at 866-394-6123 or find a clinic near you.

References

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